The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome.

Pugacheva, Elena N

The focal adhesion scaffolding protein HEF1 regulates activation of the Aurora-A and Nek2 kinases at the centrosome. [electronic resource] - Nature cell biology Oct 2005 - 937-46 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

1465-7392

10.1038/ncb1309 doi


Adaptor Proteins, Signal Transducing
Aurora Kinases
Cell Cycle--physiology
Cell Line, Tumor
Centrosome--metabolism
Enzyme Activation--physiology
Focal Adhesions--physiology
HeLa Cells
Humans
NIMA-Related Kinases
Phosphoproteins--biosynthesis
Protein Serine-Threonine Kinases--metabolism
Spindle Apparatus--metabolism