8-chloroadenosine induced HL-60 cell growth inhibition, differentiation, and G(0)/G(1) arrest involves attenuated cyclin D1 and telomerase and up-regulated p21(WAF1/CIP1).

Zhu, Bing

8-chloroadenosine induced HL-60 cell growth inhibition, differentiation, and G(0)/G(1) arrest involves attenuated cyclin D1 and telomerase and up-regulated p21(WAF1/CIP1). [electronic resource] - Journal of cellular biochemistry Jan 2006 - 166-77 p. digital

Publication Type: Journal Article

0730-2312

10.1002/jcb.20630 doi


2-Chloroadenosine--analogs & derivatives
Apoptosis--drug effects
Blotting, Western
Cell Differentiation--drug effects
Cell Division--drug effects
Cyclin D1--metabolism
Cyclin-Dependent Kinase Inhibitor p21--metabolism
Enzyme-Linked Immunosorbent Assay
Flow Cytometry
G1 Phase--drug effects
HL-60 Cells
Humans
Resting Phase, Cell Cycle--drug effects
Telomerase--metabolism