Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa.

Matsumoto, Kenjiro

Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa. [electronic resource] - Life sciences Nov 2005 - 2-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0024-3205

10.1016/j.lfs.2004.10.086 doi


Analgesics
Analgesics, Opioid--pharmacology
Animals
Dose-Response Relationship, Drug
Drug Tolerance
Injections, Subcutaneous
Male
Mice
Mitragyna--adverse effects
Models, Molecular
Morphinans--pharmacology
Morphine--antagonists & inhibitors
Naloxone--pharmacology
Naltrexone--analogs & derivatives
Narcotic Antagonists--pharmacology
Pain Measurement--drug effects
Reaction Time--drug effects
Secologanin Tryptamine Alkaloids--adverse effects
Substance Withdrawal Syndrome--psychology
Thailand