Jararhagin, a snake venom metalloproteinase, induces a specialized form of apoptosis (anoikis) selective to endothelial cells.

Tanjoni, I

Jararhagin, a snake venom metalloproteinase, induces a specialized form of apoptosis (anoikis) selective to endothelial cells. [electronic resource] - Apoptosis : an international journal on programmed cell death Aug 2005 - 851-61 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1360-8185

10.1007/s10495-005-2945-1 doi


Actins--metabolism
Animals
Anoikis--drug effects
Bothrops
Caspase 3--metabolism
Cell Adhesion--drug effects
Cell Line
Cell Line, Transformed
Cell Shape--drug effects
Cell Survival--drug effects
Crotalid Venoms--pharmacology
Cytoskeleton--drug effects
Endothelial Cells--cytology
Focal Adhesion Protein-Tyrosine Kinases--metabolism
Kinetics
Male
Metalloendopeptidases--pharmacology
Metalloproteases--pharmacology
Mice
Mice, Inbred BALB C
Phosphorylation--drug effects
Snake Venoms--enzymology
bcl-2-Associated X Protein--metabolism
bcl-X Protein--metabolism
Bothrops jararaca Venom