Synergistic apoptosis induction by proteasome and histone deacetylase inhibitors is dependent on protein synthesis.

Drexler, H C A

Synergistic apoptosis induction by proteasome and histone deacetylase inhibitors is dependent on protein synthesis. [electronic resource] - Apoptosis : an international journal on programmed cell death Aug 2005 - 743-58 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1360-8185

10.1007/s10495-005-2942-4 doi


Animals
Apoptosis--drug effects
BH3 Interacting Domain Death Agonist Protein--metabolism
Butyrates--pharmacology
Caspase 8--metabolism
Cycloheximide--pharmacology
Enzyme Activation--drug effects
Enzyme Inhibitors--pharmacology
Fusion Proteins, bcr-abl--metabolism
Histone Deacetylase Inhibitors
Humans
Hydroxamic Acids--pharmacology
K562 Cells
Mice
Mitochondria--drug effects
Oligopeptides--pharmacology
Proteasome Inhibitors
Protein Biosynthesis--drug effects
U937 Cells
Vorinostat
fas Receptor--metabolism