Cleavage of claspin by caspase-7 during apoptosis inhibits the Chk1 pathway.

Clarke, Catriona A L

Cleavage of claspin by caspase-7 during apoptosis inhibits the Chk1 pathway. [electronic resource] - The Journal of biological chemistry Oct 2005 - 35337-45 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M506460200 doi


Adaptor Proteins, Signal Transducing--chemistry
Amino Acid Motifs
Amino Acid Sequence
Animals
Apoptosis
Aspartic Acid--chemistry
Binding Sites
Caspase 7
Caspases--chemistry
Cell Cycle
Cell Line
Cell Nucleus--metabolism
Cell-Free System
Checkpoint Kinase 1
Cycloheximide--pharmacology
Cytosol--metabolism
DNA--chemistry
DNA Replication
Dose-Response Relationship, Drug
Drosophila
Etoposide--pharmacology
HeLa Cells
Humans
Immunoprecipitation
Jurkat Cells
Mice
Models, Biological
Molecular Sequence Data
Oligonucleotides--chemistry
Phosphorylation
Protein Binding
Protein Kinases--metabolism
Protein Structure, Tertiary
Protein Synthesis Inhibitors--pharmacology
Recombinant Proteins--chemistry
Sequence Homology, Amino Acid
Signal Transduction
Time Factors
Xenopus
Xenopus Proteins