MAPK/AP-1 signal pathway in tobacco smoke-induced cell proliferation and squamous metaplasia in the lungs of rats.

Zhong, Cai-Yun

MAPK/AP-1 signal pathway in tobacco smoke-induced cell proliferation and squamous metaplasia in the lungs of rats. [electronic resource] - Carcinogenesis Dec 2005 - 2187-95 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

0143-3334

10.1093/carcin/bgi189 doi


Animals
Cell Proliferation--drug effects
Cyclin D1--metabolism
Enzyme Activation--drug effects
Filaggrin Proteins
Hyperplasia--etiology
Intermediate Filament Proteins--metabolism
JNK Mitogen-Activated Protein Kinases--metabolism
Keratins--metabolism
Lung Neoplasms--etiology
Male
Membrane Proteins--metabolism
Metaplasia--etiology
Mitogen-Activated Protein Kinases--metabolism
Phosphorylation
Proliferating Cell Nuclear Antigen--metabolism
Protein Precursors--metabolism
Proto-Oncogene Proteins c-fos--metabolism
Proto-Oncogene Proteins c-jun--metabolism
Rats
Rats, Inbred WKY
Signal Transduction--drug effects
Smoking
Transcription Factor AP-1--metabolism
p38 Mitogen-Activated Protein Kinases--metabolism