JBMR anniversary classic. Nitrogen-containing biophosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. Originally published in Volume 7, number 4, pp 581-9 (1998).
Luckman, Steven P
JBMR anniversary classic. Nitrogen-containing biophosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. Originally published in Volume 7, number 4, pp 581-9 (1998). [electronic resource] - Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Jul 2005 - 1265-74 p. digital
Publication Type: Biography; Classical Article; Historical Article; Journal Article
0884-0431
10.1359/jbmr.2005.20.7.1265 doi
Animals
Bone Resorption--history
Cells, Cultured
Diphosphonates--history
GTP-Binding Proteins--history
History, 20th Century
Lovastatin--analogs & derivatives
Mevalonic Acid--history
Mice
Osteoclasts--drug effects
Protein Prenylation--drug effects
ras Proteins--history
JBMR anniversary classic. Nitrogen-containing biophosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. Originally published in Volume 7, number 4, pp 581-9 (1998). [electronic resource] - Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research Jul 2005 - 1265-74 p. digital
Publication Type: Biography; Classical Article; Historical Article; Journal Article
0884-0431
10.1359/jbmr.2005.20.7.1265 doi
Animals
Bone Resorption--history
Cells, Cultured
Diphosphonates--history
GTP-Binding Proteins--history
History, 20th Century
Lovastatin--analogs & derivatives
Mevalonic Acid--history
Mice
Osteoclasts--drug effects
Protein Prenylation--drug effects
ras Proteins--history