Presenilins mediate phosphatidylinositol 3-kinase/AKT and ERK activation via select signaling receptors. Selectivity of PS2 in platelet-derived growth factor signaling.
Kang, David E
Presenilins mediate phosphatidylinositol 3-kinase/AKT and ERK activation via select signaling receptors. Selectivity of PS2 in platelet-derived growth factor signaling. [electronic resource] - The Journal of biological chemistry Sep 2005 - 31537-47 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M500833200 doi
Amyloid Precursor Protein Secretases
Aspartic Acid Endopeptidases--physiology
Cell Line
Endopeptidases
Enzyme Activation--genetics
Extracellular Signal-Regulated MAP Kinases--metabolism
Gene Deletion
Humans
Membrane Proteins--deficiency
Phosphatidylinositol 3-Kinases--metabolism
Platelet-Derived Growth Factor--physiology
Presenilin-1
Presenilin-2
Protein Serine-Threonine Kinases--metabolism
Proto-Oncogene Proteins--metabolism
Proto-Oncogene Proteins c-akt
Signal Transduction--genetics
Presenilins mediate phosphatidylinositol 3-kinase/AKT and ERK activation via select signaling receptors. Selectivity of PS2 in platelet-derived growth factor signaling. [electronic resource] - The Journal of biological chemistry Sep 2005 - 31537-47 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M500833200 doi
Amyloid Precursor Protein Secretases
Aspartic Acid Endopeptidases--physiology
Cell Line
Endopeptidases
Enzyme Activation--genetics
Extracellular Signal-Regulated MAP Kinases--metabolism
Gene Deletion
Humans
Membrane Proteins--deficiency
Phosphatidylinositol 3-Kinases--metabolism
Platelet-Derived Growth Factor--physiology
Presenilin-1
Presenilin-2
Protein Serine-Threonine Kinases--metabolism
Proto-Oncogene Proteins--metabolism
Proto-Oncogene Proteins c-akt
Signal Transduction--genetics