Long-term treatment with rosiglitazone and metformin reduces the extent of, but does not prevent, islet amyloid deposition in mice expressing the gene for human islet amyloid polypeptide.

Hull, Rebecca L

Long-term treatment with rosiglitazone and metformin reduces the extent of, but does not prevent, islet amyloid deposition in mice expressing the gene for human islet amyloid polypeptide. [electronic resource] - Diabetes Jul 2005 - 2235-44 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0012-1797

10.2337/diabetes.54.7.2235 doi


Amyloid--genetics
Animals
Gene Expression Regulation--drug effects
Humans
Islet Amyloid Polypeptide
Islets of Langerhans--drug effects
Metformin--pharmacology
Mice
Mice, Transgenic
Rosiglitazone
Thiazolidinediones--pharmacology