Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib.

Haas-Kogan, Daphne A

Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib. [electronic resource] - Journal of the National Cancer Institute Jun 2005 - 880-7 p. digital

Publication Type: Clinical Trial; Clinical Trial, Phase I; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1460-2105

10.1093/jnci/dji161 doi


Adult
Aged
Antineoplastic Agents--administration & dosage
Antineoplastic Combined Chemotherapy Protocols--therapeutic use
Area Under Curve
Dacarbazine--administration & dosage
Drug Administration Schedule
Drug Resistance, Neoplasm
ErbB Receptors--drug effects
Erlotinib Hydrochloride
Female
Glioma--drug therapy
Humans
Immunohistochemistry
In Situ Hybridization, Fluorescence
Male
Middle Aged
Mutation
PTEN Phosphohydrolase
Phosphoric Monoester Hydrolases--drug effects
Phosphorylation
Protein Serine-Threonine Kinases--antagonists & inhibitors
Proto-Oncogene Proteins--antagonists & inhibitors
Proto-Oncogene Proteins c-akt
Quinazolines--administration & dosage
Supratentorial Neoplasms--drug therapy
Temozolomide
Tumor Suppressor Proteins--drug effects