Mu-opioid receptor and CREB activation are required for nicotine reward.

Walters, Carrie L

Mu-opioid receptor and CREB activation are required for nicotine reward. [electronic resource] - Neuron Jun 2005 - 933-43 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.

0896-6273

10.1016/j.neuron.2005.05.005 doi


Analysis of Variance
Anesthetics, Local--pharmacology
Animals
Behavior, Animal--drug effects
Blotting, Northern--methods
Blotting, Western--methods
Brain--cytology
Cell Count--methods
Cocaine--pharmacology
Conditioning, Operant--drug effects
Cyclic AMP Response Element-Binding Protein--genetics
Dose-Response Relationship, Drug
Drug Interactions
Enzyme Activation--drug effects
Immunohistochemistry--methods
Immunoprecipitation--methods
Mice
Mice, Inbred C57BL
Mice, Knockout
Naloxone--pharmacology
Narcotic Antagonists--pharmacology
Neurons--drug effects
Nicotine--adverse effects
Phosphorylation--drug effects
RNA, Messenger--metabolism
Receptors, Opioid, mu--deficiency
Reverse Transcriptase Polymerase Chain Reaction--methods
Reward
Time Factors
Tobacco Use Disorder--etiology