Pharmacologic manipulation of the ataxia-telangiectasia mutated gene product as an intervention in age-related disease.

Shackelford, Rodney E

Pharmacologic manipulation of the ataxia-telangiectasia mutated gene product as an intervention in age-related disease. [electronic resource] - Medical hypotheses 2005 - 363-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0306-9877

10.1016/j.mehy.2005.02.015 doi


Aging
Animals
Antioxidants--metabolism
Ataxia Telangiectasia Mutated Proteins
Catechin--analogs & derivatives
Cell Cycle Proteins--genetics
DNA-Binding Proteins--genetics
Enzyme Inhibitors--pharmacology
Genistein--pharmacology
Humans
Insulin-Like Growth Factor I--metabolism
Mice
Models, Biological
Models, Theoretical
Mutation
Oxidants--metabolism
Protein Serine-Threonine Kinases--genetics
Quercetin--pharmacology
Signal Transduction
Tumor Suppressor Protein p53--metabolism
Tumor Suppressor Proteins--genetics