The protective effect of dantrolene on ischemic neuronal cell death is associated with reduced expression of endoplasmic reticulum stress markers.

Li, Feng

The protective effect of dantrolene on ischemic neuronal cell death is associated with reduced expression of endoplasmic reticulum stress markers. [electronic resource] - Brain research Jun 2005 - 59-68 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0006-8993

10.1016/j.brainres.2005.04.058 doi


Activating Transcription Factor 4
Analysis of Variance
Animals
Blotting, Western--methods
CCAAT-Enhancer-Binding Proteins--metabolism
Cell Count--methods
Cell Death--drug effects
Dantrolene--therapeutic use
Disease Models, Animal
Endoplasmic Reticulum--drug effects
Eukaryotic Initiation Factor-2--metabolism
Gene Expression Regulation--drug effects
Glial Fibrillary Acidic Protein--metabolism
Immunohistochemistry--methods
In Situ Nick-End Labeling--methods
Infarction, Middle Cerebral Artery--complications
Ischemia--etiology
Male
Muscle Relaxants, Central--therapeutic use
Neurons--drug effects
Phosphopyruvate Hydratase--metabolism
Phosphorylation
Rats
Rats, Wistar
Reperfusion--methods
Time Factors
Transcription Factor CHOP
Transcription Factors--metabolism
eIF-2 Kinase--metabolism