The Ins2Akita mouse as a model of early retinal complications in diabetes.

Barber, Alistair J

The Ins2Akita mouse as a model of early retinal complications in diabetes. [electronic resource] - Investigative ophthalmology & visual science Jun 2005 - 2210-8 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0146-0404

10.1167/iovs.04-1340 doi


Animals
Apoptosis
Astrocytes--metabolism
Blood Glucose--metabolism
Body Weight
Capillary Permeability
Caspase 3
Caspases--metabolism
Diabetes Mellitus, Type 1--genetics
Diabetic Retinopathy--genetics
Disease Models, Animal
Glial Fibrillary Acidic Protein--metabolism
Hyperglycemia--pathology
Insulin--genetics
Male
Mice
Mice, Inbred C57BL
Microscopy, Confocal
Neuroglia--metabolism
Receptor, Insulin--metabolism
Retinal Degeneration
Retinal Vessels--pathology