Decreased PARP and procaspase-2 protein levels are associated with cellular drug resistance in childhood acute lymphoblastic leukemia.

Holleman, Amy

Decreased PARP and procaspase-2 protein levels are associated with cellular drug resistance in childhood acute lymphoblastic leukemia. [electronic resource] - Blood Sep 2005 - 1817-23 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0006-4971

10.1182/blood-2004-11-4296 doi


Apoptosis--physiology
Caspase 2
Caspases--genetics
Cell Line, Tumor
Child
Drug Resistance, Neoplasm--physiology
Drug Screening Assays, Antitumor
Gene Expression Regulation, Enzymologic
Humans
Poly(ADP-ribose) Polymerases--genetics
Precursor Cell Lymphoblastic Leukemia-Lymphoma--metabolism
RNA, Messenger--genetics