Design and synthesis of novel diphenacoum-derived, conformation-restricted vitamin K 2,3-epoxide reductase inhibitors.

Chen, Ding-Uei

Design and synthesis of novel diphenacoum-derived, conformation-restricted vitamin K 2,3-epoxide reductase inhibitors. [electronic resource] - Bioorganic & medicinal chemistry letters May 2005 - 2665-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0960-894X

10.1016/j.bmcl.2005.03.005 doi


Animals
Cattle
Coumarins--chemistry
Crystallography, X-Ray
Enzyme Inhibitors--chemical synthesis
Liver--enzymology
Mixed Function Oxygenases--antagonists & inhibitors
Molecular Conformation
Vitamin K Epoxide Reductases