Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells.

Xu, Changjiang

Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells. [electronic resource] - Oncogene Jun 2005 - 4486-95 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.

0950-9232

10.1038/sj.onc.1208656 doi


Anticarcinogenic Agents--pharmacology
Cell Line, Tumor
Cell Survival--drug effects
Cyclin D1--drug effects
Enzyme Inhibitors--pharmacology
Gene Expression Regulation, Neoplastic--drug effects
Humans
I-kappa B Kinase
I-kappa B Proteins--drug effects
Isothiocyanates--pharmacology
Male
NF-KappaB Inhibitor alpha
NF-kappa B--drug effects
Phosphorylation
Prostatic Neoplasms--drug therapy
Protein Serine-Threonine Kinases--antagonists & inhibitors
Proto-Oncogene Proteins c-bcl-2--drug effects
Sulfoxides
Thiocyanates--pharmacology
Transcription, Genetic
Vascular Endothelial Growth Factor A--drug effects
bcl-X Protein