Mechanism-based inactivation of dihydropyrimidine dehydrogenase by 5-ethynyluracil.

Porter, D J

Mechanism-based inactivation of dihydropyrimidine dehydrogenase by 5-ethynyluracil. [electronic resource] - The Journal of biological chemistry Mar 1992 - 5236-42 p. digital

Publication Type: Journal Article

0021-9258


Amino Acid Sequence
Animals
Cattle
Dihydrouracil Dehydrogenase (NADP)
Dithiothreitol--pharmacology
Humans
Kinetics
Liver--enzymology
Mathematics
Mice
Molecular Sequence Data
Oxidoreductases--antagonists & inhibitors
Peptide Fragments--isolation & purification
Rats
Structure-Activity Relationship
Uracil--analogs & derivatives