In vivo, nucleoside reverse-transcriptase inhibitors alter expression of both mitochondrial and lipid metabolism genes in the absence of depletion of mitochondrial DNA.

Mallon, Patrick W G

In vivo, nucleoside reverse-transcriptase inhibitors alter expression of both mitochondrial and lipid metabolism genes in the absence of depletion of mitochondrial DNA. [electronic resource] - The Journal of infectious diseases May 2005 - 1686-96 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0022-1899

10.1086/429697 doi


Adipose Tissue--drug effects
Adult
Aged
Body Composition--drug effects
DNA, Mitochondrial--metabolism
Female
Gene Expression--drug effects
Humans
Lipid Metabolism
Male
Middle Aged
Mitochondria--drug effects
Reverse Transcriptase Inhibitors--pharmacology
Up-Regulation