Inhibition of neuronal apoptosis by the cyclin-dependent kinase inhibitor GW8510: identification of 3' substituted indolones as a scaffold for the development of neuroprotective drugs.

Johnson, Kyle

Inhibition of neuronal apoptosis by the cyclin-dependent kinase inhibitor GW8510: identification of 3' substituted indolones as a scaffold for the development of neuroprotective drugs. [electronic resource] - Journal of neurochemistry May 2005 - 538-48 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0022-3042

10.1111/j.1471-4159.2004.03004.x doi


Animals
Apoptosis--drug effects
Cell Line
Cyclin-Dependent Kinases--antagonists & inhibitors
Dose-Response Relationship, Drug
Indoles--chemistry
Neurons--drug effects
Neuroprotective Agents--chemistry
Protein Kinase Inhibitors--chemistry
Rats
Rats, Wistar