Kynurenine 3-mono-oxygenase inhibitors reduce glutamate concentration in the extracellular spaces of the basal ganglia but not in those of the cortex or hippocampus.

Moroni, F

Kynurenine 3-mono-oxygenase inhibitors reduce glutamate concentration in the extracellular spaces of the basal ganglia but not in those of the cortex or hippocampus. [electronic resource] - Neuropharmacology May 2005 - 788-95 p. digital

Publication Type: Comparative Study; Journal Article

0028-3908

10.1016/j.neuropharm.2004.10.019 doi


Animals
Avoidance Learning--drug effects
Basal Ganglia--drug effects
Behavior, Animal--drug effects
Brain Chemistry--drug effects
Calcium Channel Blockers--pharmacology
Chromatography, High Pressure Liquid--methods
Dose-Response Relationship, Drug
Drug Interactions
Extracellular Space--drug effects
Glutamic Acid--metabolism
Kynurenic Acid--metabolism
Kynurenine 3-Monooxygenase
Male
Microdialysis--methods
Mixed Function Oxygenases--antagonists & inhibitors
Potassium Chloride--pharmacology
Rats
Rats, Wistar
Statistics, Nonparametric
Sulfonamides--pharmacology
Thiazoles--pharmacology
Time Factors
omega-Conotoxin GVIA--pharmacology