Application of stereocontrolled stepwise [3+2] cycloadditions to the preparation of inhibitors of alpha4beta1-integrin-mediated hepatic melanoma metastasis.

Zubia, Aizpea

Application of stereocontrolled stepwise [3+2] cycloadditions to the preparation of inhibitors of alpha4beta1-integrin-mediated hepatic melanoma metastasis. [electronic resource] - Angewandte Chemie (International ed. in English) May 2005 - 2903-7 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1433-7851

10.1002/anie.200462497 doi


Animals
Antineoplastic Agents--chemical synthesis
Crystallography, X-Ray
Cyclization
Drug Design
Integrin alpha4beta1--antagonists & inhibitors
Liver Neoplasms--drug therapy
Male
Melanoma--drug therapy
Mice
Mice, Inbred C57BL
Molecular Structure
Stereoisomerism