Ku protein targeting by Ku70 small interfering RNA enhances human cancer cell response to topoisomerase II inhibitor and gamma radiation.

Ayene, Iraimoudi S

Ku protein targeting by Ku70 small interfering RNA enhances human cancer cell response to topoisomerase II inhibitor and gamma radiation. [electronic resource] - Molecular cancer therapeutics Apr 2005 - 529-36 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.

1535-7163

10.1158/1535-7163.MCT-04-0130 doi


Animals
Antigens, Nuclear--genetics
Antineoplastic Agents, Phytogenic--pharmacology
Apoptosis
Blotting, Western
Cell Line, Tumor
Cricetinae
DNA Damage
DNA Repair
DNA-Binding Proteins--genetics
Dimerization
Dose-Response Relationship, Radiation
Etoposide--pharmacology
Gamma Rays
HeLa Cells
Humans
Ku Autoantigen
Microscopy, Fluorescence
Neoplasms--therapy
Phenotype
RNA, Messenger--metabolism
RNA, Small Interfering--genetics
Telomere--ultrastructure
Time Factors
Topoisomerase II Inhibitors
Transfection
VDJ Recombinases--metabolism