Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung.

Thomas, Mini

Full deacylation of polyethylenimine dramatically boosts its gene delivery efficiency and specificity to mouse lung. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Apr 2005 - 5679-84 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0027-8424

10.1073/pnas.0502067102 doi


Acylation
Animals
Cell Line, Tumor
Gene Expression Regulation
Gene Transfer Techniques
Humans
Influenza, Human--drug therapy
Lung--metabolism
Mice
Orthomyxoviridae--drug effects
Polyethyleneimine--chemistry
RNA, Small Interfering--genetics