Chymotrypsin-like proteases contribute to human monocytic THP-1 cell as well as human microglial neurotoxicity.

Klegeris, Andis

Chymotrypsin-like proteases contribute to human monocytic THP-1 cell as well as human microglial neurotoxicity. [electronic resource] - Glia Jul 2005 - 56-64 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0894-1491

10.1002/glia.20186 doi


Cell Line
Cell Survival--drug effects
Cells, Cultured
Chymotrypsin--physiology
Humans
Hydrogen Peroxide--pharmacology
Interferon-gamma--pharmacology
L-Lactate Dehydrogenase--metabolism
Microglia--drug effects
Monocytes--drug effects
Neurotoxicity Syndromes--pathology
Serine Proteinase Inhibitors--pharmacology
Stimulation, Chemical
Subcellular Fractions--chemistry
Temporal Lobe--cytology
Tetrazolium Salts
Thiazoles
Tumor Necrosis Factor-alpha--pharmacology