Design and optimization of tricyclic phtalimide analogues as novel inhibitors of HIV-1 integrase.

Verschueren, Wim G

Design and optimization of tricyclic phtalimide analogues as novel inhibitors of HIV-1 integrase. [electronic resource] - Journal of medicinal chemistry Mar 2005 - 1930-40 p. digital

Publication Type: Journal Article

0022-2623

10.1021/jm049559q doi


Anti-HIV Agents--chemical synthesis
Binding Sites
Cell Line
HIV Integrase--chemistry
HIV Integrase Inhibitors--chemical synthesis
HIV-1--drug effects
Heterocyclic Compounds, 3-Ring--chemical synthesis
Humans
Models, Molecular
Phthalimides--chemical synthesis
Protein Binding
Pyrroles--chemical synthesis
Quinoxalines--chemical synthesis
Structure-Activity Relationship