Development of a multivariate statistical model to predict peroxisome proliferation in the rat, based on urinary 1H-NMR spectral patterns.

Connor, Susan C

Development of a multivariate statistical model to predict peroxisome proliferation in the rat, based on urinary 1H-NMR spectral patterns. [electronic resource] - Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 364-85 p. digital

Publication Type: Journal Article

1354-750X

10.1080/13547500400006005 doi


Animals
Body Weight--drug effects
Carboxy-Lyases--biosynthesis
Down-Regulation
Fenofibrate--metabolism
Liver--drug effects
Magnetic Resonance Spectroscopy
Male
Models, Statistical
Multivariate Analysis
Organ Size--drug effects
Pentosyltransferases--biosynthesis
Peroxisome Proliferator-Activated Receptors--agonists
Peroxisome Proliferators--metabolism
Peroxisomes--drug effects
Random Allocation
Rats
Rats, Sprague-Dawley
Rats, Wistar
Up-Regulation
Nicotinate-Nucleotide Diphosphorylase (Carboxylating)