Plasmid vaccination of stable HIV-positive subjects on antiviral treatment results in enhanced CD8 T-cell immunity and increased control of viral "blips".

MacGregor, Rob Roy

Plasmid vaccination of stable HIV-positive subjects on antiviral treatment results in enhanced CD8 T-cell immunity and increased control of viral "blips". [electronic resource] - Vaccine Mar 2005 - 2066-73 p. digital

Publication Type: Clinical Trial; Clinical Trial, Phase I; Controlled Clinical Trial; Journal Article; Research Support, U.S. Gov't, P.H.S.

0264-410X

10.1016/j.vaccine.2005.01.010 doi


AIDS Vaccines--genetics
Adult
Antiretroviral Therapy, Highly Active
CD4 Lymphocyte Count
CD8-Positive T-Lymphocytes--immunology
Double-Blind Method
Female
HIV Antibodies--biosynthesis
HIV Seropositivity--drug therapy
Humans
Male
Middle Aged
Plasmids--genetics
RNA, Viral--blood
Safety
Vaccines, DNA--genetics
Viremia--drug therapy