Spinal p38beta isoform mediates tissue injury-induced hyperalgesia and spinal sensitization.

Svensson, Camilla I

Spinal p38beta isoform mediates tissue injury-induced hyperalgesia and spinal sensitization. [electronic resource] - Journal of neurochemistry Mar 2005 - 1508-20 p. digital

Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.

0022-3042

10.1111/j.1471-4159.2004.02996.x doi


Animals
Down-Regulation--drug effects
Hyperalgesia--metabolism
Injections, Spinal
Male
Microglia--metabolism
Mitogen-Activated Protein Kinase 11--antagonists & inhibitors
Mitogen-Activated Protein Kinase 14--antagonists & inhibitors
Oligoribonucleotides, Antisense
Pain--metabolism
Pain Measurement--drug effects
Posterior Horn Cells--metabolism
Protein Isoforms--antagonists & inhibitors
Rats
Rats, Sprague-Dawley
Receptors, Neurokinin-1--drug effects
Spinal Cord--metabolism
Substance P--metabolism