Artificial zinc finger fusions targeting Sp1-binding sites and the trans-activator-responsive element potently repress transcription and replication of HIV-1.

Kim, Yeon-Soo

Artificial zinc finger fusions targeting Sp1-binding sites and the trans-activator-responsive element potently repress transcription and replication of HIV-1. [electronic resource] - The Journal of biological chemistry Jun 2005 - 21545-52 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9258

10.1074/jbc.M414136200 doi


Binding Sites
Cell Line
Cell-Free System
Chloramphenicol O-Acetyltransferase--metabolism
Cyclin T
Cyclins--chemistry
Gene Deletion
Gene Products, tat--metabolism
HIV
HIV-1--metabolism
HeLa Cells
Humans
Models, Biological
Mutation
Peptides--chemistry
Plasmids--metabolism
Polymerase Chain Reaction
Promoter Regions, Genetic
Protein Binding
Protein Structure, Tertiary
RNA Polymerase II--chemistry
Recombinant Fusion Proteins--chemistry
Sp1 Transcription Factor--metabolism
Transcription, Genetic
Transcriptional Activation
Zinc--chemistry
Zinc Fingers
tat Gene Products, Human Immunodeficiency Virus