The Wiskott-Aldrich syndrome protein regulates nuclear translocation of NFAT2 and NF-kappa B (RelA) independently of its role in filamentous actin polymerization and actin cytoskeletal rearrangement.

Huang, Winifred

The Wiskott-Aldrich syndrome protein regulates nuclear translocation of NFAT2 and NF-kappa B (RelA) independently of its role in filamentous actin polymerization and actin cytoskeletal rearrangement. [electronic resource] - Journal of immunology (Baltimore, Md. : 1950) Mar 2005 - 2602-11 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0022-1767

10.4049/jimmunol.174.5.2602 doi


Actins--metabolism
Active Transport, Cell Nucleus--genetics
Cell Communication--genetics
Cell Line, Transformed
Cell Nucleus--metabolism
Clone Cells
Cytoskeleton--metabolism
Cytotoxicity, Immunologic--genetics
DNA-Binding Proteins--metabolism
Granulocyte-Macrophage Colony-Stimulating Factor--antagonists & inhibitors
Humans
Interferon-gamma--biosynthesis
Killer Cells, Natural--enzymology
Lymphocyte Activation--genetics
Membrane Glycoproteins--physiology
Membrane Microdomains--enzymology
NF-kappa B--metabolism
NFATC Transcription Factors
Natural Cytotoxicity Triggering Receptor 1
Nuclear Proteins--metabolism
Phospholipase C gamma
Proteins--genetics
Receptors, Immunologic--physiology
Signal Transduction--genetics
Transcription Factor RelA
Transcription Factors--metabolism
Type C Phospholipases--antagonists & inhibitors
Wiskott-Aldrich Syndrome--genetics
Wiskott-Aldrich Syndrome Protein