Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification.

Pegan, Scott

Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification. [electronic resource] - Nature neuroscience Mar 2005 - 279-87 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

1097-6256

10.1038/nn1411 doi


Amino Acid Sequence
Analysis of Variance
Animals
Cloning, Molecular--methods
Crystallography--methods
Dose-Response Relationship, Drug
Electric Conductivity
G Protein-Coupled Inwardly-Rectifying Potassium Channels
GTP-Binding Protein beta Subunits--genetics
Ion Channel Gating--drug effects
Macromolecular Substances
Membrane Potentials--drug effects
Molecular Sequence Data
Mutagenesis, Site-Directed--physiology
Patch-Clamp Techniques--methods
Phosphatidylinositol 4,5-Diphosphate--metabolism
Potassium--pharmacology
Potassium Channels, Inwardly Rectifying--chemistry
Protein Conformation
Protein Structure, Tertiary--physiology
Recombinant Fusion Proteins--chemistry
Xenopus laevis