Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity.
Hoet, René Michael
Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity. [electronic resource] - Nature biotechnology Mar 2005 - 344-8 p. digital
Publication Type: Letter
1087-0156
10.1038/nbt1067 doi
Antibody Affinity
Antibody Formation
Complementarity Determining Regions--genetics
Genetic Variation--genetics
Humans
Immunoglobulin Fab Fragments--biosynthesis
Peptide Library
Protein Binding
Protein Engineering--methods
Recombination, Genetic--genetics
Tissue Donors
Generation of high-affinity human antibodies by combining donor-derived and synthetic complementarity-determining-region diversity. [electronic resource] - Nature biotechnology Mar 2005 - 344-8 p. digital
Publication Type: Letter
1087-0156
10.1038/nbt1067 doi
Antibody Affinity
Antibody Formation
Complementarity Determining Regions--genetics
Genetic Variation--genetics
Humans
Immunoglobulin Fab Fragments--biosynthesis
Peptide Library
Protein Binding
Protein Engineering--methods
Recombination, Genetic--genetics
Tissue Donors