The role of checkpoint kinase 1 in sensitivity to topoisomerase I poisons.

Flatten, Karen

The role of checkpoint kinase 1 in sensitivity to topoisomerase I poisons. [electronic resource] - The Journal of biological chemistry Apr 2005 - 14349-55 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M411890200 doi


Antineoplastic Agents, Phytogenic--metabolism
Ataxia Telangiectasia Mutated Proteins
Camptothecin--analogs & derivatives
Cell Cycle Proteins--genetics
Cell Line
Checkpoint Kinase 1
Checkpoint Kinase 2
DNA Topoisomerases, Type I--metabolism
Gene Deletion
Genes, cdc
HSP90 Heat-Shock Proteins--antagonists & inhibitors
Humans
Neoplasms--drug therapy
Protein Kinases--genetics
Protein Serine-Threonine Kinases--genetics
RNA, Small Interfering--genetics
Topoisomerase I Inhibitors