Application of Rho antagonist to neuronal cell bodies promotes neurite growth in compartmented cultures and regeneration of retinal ganglion cell axons in the optic nerve of adult rats.

Bertrand, Johanne

Application of Rho antagonist to neuronal cell bodies promotes neurite growth in compartmented cultures and regeneration of retinal ganglion cell axons in the optic nerve of adult rats. [electronic resource] - The Journal of neuroscience : the official journal of the Society for Neuroscience Feb 2005 - 1113-21 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1529-2401

10.1523/JNEUROSCI.3931-04.2005 doi


ADP Ribose Transferases--administration & dosage
Animals
Axons--drug effects
Cell Survival
Cells, Cultured--drug effects
Cicatrix--pathology
Culture Media
Cytoskeletal Proteins--metabolism
Female
Injections
Microsurgery
Myelin-Associated Glycoprotein
Nerve Crush
Nerve Regeneration--drug effects
Nerve Tissue Proteins--metabolism
Neurites--physiology
Neuroprotective Agents--administration & dosage
Optic Nerve--drug effects
Optic Nerve Injuries--drug therapy
Rats
Rats, Sprague-Dawley
Retinal Ganglion Cells--drug effects
Superior Cervical Ganglion--cytology
Vitreous Body
rho GTP-Binding Proteins--antagonists & inhibitors