Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3beta phosphorylation of CRMP2: implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease.

Uchida, Yutaka

Semaphorin3A signalling is mediated via sequential Cdk5 and GSK3beta phosphorylation of CRMP2: implication of common phosphorylating mechanism underlying axon guidance and Alzheimer's disease. [electronic resource] - Genes to cells : devoted to molecular & cellular mechanisms Feb 2005 - 165-79 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1356-9597

10.1111/j.1365-2443.2005.00827.x doi


Alzheimer Disease--metabolism
Amino Acid Sequence
Animals
Axons--pathology
Cells, Cultured
Cyclin-Dependent Kinase 5--genetics
Ganglia, Spinal--cytology
Glycogen Synthase Kinase 3--genetics
Glycogen Synthase Kinase 3 beta
Growth Cones--metabolism
Humans
Intercellular Signaling Peptides and Proteins
Mice
Mice, Inbred C57BL
Mice, Knockout
Molecular Sequence Data
Nerve Tissue Proteins--genetics
Neurons--cytology
Phosphorylation
Protein Binding
RNA, Small Interfering--metabolism
Semaphorin-3A--genetics
Signal Transduction
Tubulin--metabolism