Ethylmorphine O-deethylation cosegregates with the debrisoquin genetic metabolic polymorphism.

Rane, A

Ethylmorphine O-deethylation cosegregates with the debrisoquin genetic metabolic polymorphism. [electronic resource] - Clinical pharmacology and therapeutics Sep 1992 - 257-64 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0009-9236

10.1038/clpt.1992.139 doi


Adult
Chromatography, High Pressure Liquid
Dealkylation
Debrisoquin--pharmacokinetics
Dextromethorphan--metabolism
Ethylmorphine--metabolism
Female
Humans
Male
Metabolic Clearance Rate
Metabolism--genetics
Middle Aged
Polymorphism, Genetic
Regression Analysis