The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma.

Slack, Andrew

The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma. [electronic resource] - Proceedings of the National Academy of Sciences of the United States of America Jan 2005 - 731-6 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0027-8424

10.1073/pnas.0405495102 doi


Apoptosis
Cell Line, Tumor
E-Box Elements
Gene Expression Regulation, Neoplastic
Humans
N-Myc Proto-Oncogene Protein
Neuroblastoma--etiology
Nuclear Proteins--analysis
Oncogene Proteins--physiology
Promoter Regions, Genetic
Proto-Oncogene Proteins--analysis
Proto-Oncogene Proteins c-mdm2
RNA, Messenger--analysis
Transcription, Genetic
Tumor Suppressor Protein p53--antagonists & inhibitors