Small interfering RNA inhibition of SPARC attenuates the profibrotic effect of transforming growth factor beta1 in cultured normal human fibroblasts.

Zhou, Xiaodong

Small interfering RNA inhibition of SPARC attenuates the profibrotic effect of transforming growth factor beta1 in cultured normal human fibroblasts. [electronic resource] - Arthritis and rheumatism Jan 2005 - 257-61 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0004-3591

10.1002/art.20785 doi


Cells, Cultured
Collagen Type I--antagonists & inhibitors
Fibroblasts--drug effects
Fibrosis
Humans
Osteonectin--antagonists & inhibitors
RNA, Small Interfering--genetics
Skin
Transfection
Transforming Growth Factor beta--pharmacology
Transforming Growth Factor beta1