A novel mechanism for JAK2 activation by a G protein-coupled receptor, the CCK2R: implication of this signaling pathway in pancreatic tumor models.
Ferrand, Audrey
A novel mechanism for JAK2 activation by a G protein-coupled receptor, the CCK2R: implication of this signaling pathway in pancreatic tumor models. [electronic resource] - The Journal of biological chemistry Mar 2005 - 10710-5 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M413309200 doi
Amino Acid Motifs
Animals
Blotting, Western
COS Cells
Cell Line
Cell Proliferation
Culture Media, Serum-Free--pharmacology
DNA, Complementary--metabolism
DNA-Binding Proteins--metabolism
Enzyme Activation
Homozygote
Immunohistochemistry
Inositol 1,4,5-Trisphosphate--chemistry
Janus Kinase 2
Mice
Mice, Transgenic
Microscopy, Fluorescence
Mutation
Pancreas--metabolism
Protein Binding
Protein-Tyrosine Kinases--chemistry
Proto-Oncogene Proteins--chemistry
Receptor, Cholecystokinin B--chemistry
STAT3 Transcription Factor
Signal Transduction
Time Factors
Trans-Activators--metabolism
Transfection
A novel mechanism for JAK2 activation by a G protein-coupled receptor, the CCK2R: implication of this signaling pathway in pancreatic tumor models. [electronic resource] - The Journal of biological chemistry Mar 2005 - 10710-5 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M413309200 doi
Amino Acid Motifs
Animals
Blotting, Western
COS Cells
Cell Line
Cell Proliferation
Culture Media, Serum-Free--pharmacology
DNA, Complementary--metabolism
DNA-Binding Proteins--metabolism
Enzyme Activation
Homozygote
Immunohistochemistry
Inositol 1,4,5-Trisphosphate--chemistry
Janus Kinase 2
Mice
Mice, Transgenic
Microscopy, Fluorescence
Mutation
Pancreas--metabolism
Protein Binding
Protein-Tyrosine Kinases--chemistry
Proto-Oncogene Proteins--chemistry
Receptor, Cholecystokinin B--chemistry
STAT3 Transcription Factor
Signal Transduction
Time Factors
Trans-Activators--metabolism
Transfection