The G972R variant of the insulin receptor substrate-1 (IRS-1) gene is associated with insulin resistance in "uncomplicated" obese subjects evaluated by hyperinsulinemic-euglycemic clamp.

Baroni, M G

The G972R variant of the insulin receptor substrate-1 (IRS-1) gene is associated with insulin resistance in "uncomplicated" obese subjects evaluated by hyperinsulinemic-euglycemic clamp. [electronic resource] - Journal of endocrinological investigation Sep 2004 - 754-9 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0391-4097

10.1007/BF03347518 doi


Adult
Female
Gene Frequency
Glucose Clamp Technique
Glucose Tolerance Test
Humans
Hyperinsulinism--blood
Hypoglycemic Agents
In Situ Hybridization, Fluorescence
Insulin--metabolism
Insulin Receptor Substrate Proteins
Insulin Resistance--genetics
Logistic Models
Male
Mutation
Obesity--genetics
Phosphoproteins--genetics
Reverse Transcriptase Polymerase Chain Reaction
Spectrometry, Fluorescence