Abnormal metabotropic glutamate receptor expression and signaling in the cerebral cortex in diffuse Lewy body disease is associated with irregular alpha-synuclein/phospholipase C (PLCbeta1) interactions.

Dalfó, E

Abnormal metabotropic glutamate receptor expression and signaling in the cerebral cortex in diffuse Lewy body disease is associated with irregular alpha-synuclein/phospholipase C (PLCbeta1) interactions. [electronic resource] - Brain pathology (Zurich, Switzerland) Oct 2004 - 388-98 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

1015-6305

10.1111/j.1750-3639.2004.tb00082.x doi


Aged
Aged, 80 and over
Cell Fractionation--methods
Cell Membrane--drug effects
Cerebral Cortex--metabolism
Dose-Response Relationship, Drug
Excitatory Amino Acid Agonists--pharmacology
Female
Glutamic Acid--pharmacokinetics
Guanosine Triphosphate--pharmacology
Humans
Immunoblotting--methods
Immunohistochemistry--methods
Immunoprecipitation--methods
Lewy Body Disease--metabolism
Male
Membrane Proteins--metabolism
Microscopy, Confocal--methods
Middle Aged
Nerve Tissue Proteins--metabolism
Postmortem Changes
Proline--analogs & derivatives
Propionates--pharmacology
Protein Binding--drug effects
Quisqualic Acid--pharmacology
Radioligand Assay--methods
Receptors, Glutamate--metabolism
Signal Transduction--physiology
Synaptosomal-Associated Protein 25
Synucleins
Tritium--pharmacokinetics
Type C Phospholipases--metabolism
alpha-Synuclein