Potential antidepressant LY 367265 presynaptically inhibits the release of glutamate in rat cerebral cortex.

Wang, Su-Jane

Potential antidepressant LY 367265 presynaptically inhibits the release of glutamate in rat cerebral cortex. [electronic resource] - Synapse (New York, N.Y.) Mar 2005 - 156-63 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

0887-4476

10.1002/syn.20104 doi


4-Aminopyridine--antagonists & inhibitors
Animals
Antidepressive Agents--pharmacology
Calcium Channels--drug effects
Calcium Signaling--drug effects
Cerebral Cortex--drug effects
Cyclic S-Oxides--pharmacology
Dose-Response Relationship, Drug
Fluoxetine--pharmacology
Glutamic Acid--metabolism
Ionomycin--pharmacology
Male
Membrane Glycoproteins--drug effects
Membrane Potentials--drug effects
Membrane Transport Proteins--drug effects
Nerve Tissue Proteins--drug effects
Presynaptic Terminals--drug effects
Rats
Rats, Sprague-Dawley
Receptor, Serotonin, 5-HT2A--drug effects
Serotonin Plasma Membrane Transport Proteins
Selective Serotonin Reuptake Inhibitors--pharmacology
Synaptic Transmission--drug effects
Synaptosomes--chemistry
Thiadiazoles--pharmacology