Drug interactions with the potential to prevent prodrug activation as a common source of irrational prescribing in hospital inpatients.
Tirkkonen, Tuire
Drug interactions with the potential to prevent prodrug activation as a common source of irrational prescribing in hospital inpatients. [electronic resource] - Clinical pharmacology and therapeutics Dec 2004 - 639-47 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0009-9236
10.1016/j.clpt.2004.08.017 doi
Adolescent
Adult
Aged
Aged, 80 and over
Analgesics, Opioid--pharmacokinetics
Antihypertensive Agents--pharmacokinetics
Aryl Hydrocarbon Hydroxylases--antagonists & inhibitors
Biotransformation--drug effects
Codeine--pharmacokinetics
Cytochrome P-450 CYP2C9
Cytochrome P-450 CYP2D6 Inhibitors
Databases, Nucleic Acid
Drug Interactions
Drug Prescriptions--economics
Enzyme Inhibitors--pharmacology
Female
Humans
Losartan--pharmacokinetics
Male
Medication Errors
Medication Systems, Hospital
Middle Aged
Prodrugs--metabolism
Sex Factors
Tramadol--pharmacokinetics
Drug interactions with the potential to prevent prodrug activation as a common source of irrational prescribing in hospital inpatients. [electronic resource] - Clinical pharmacology and therapeutics Dec 2004 - 639-47 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0009-9236
10.1016/j.clpt.2004.08.017 doi
Adolescent
Adult
Aged
Aged, 80 and over
Analgesics, Opioid--pharmacokinetics
Antihypertensive Agents--pharmacokinetics
Aryl Hydrocarbon Hydroxylases--antagonists & inhibitors
Biotransformation--drug effects
Codeine--pharmacokinetics
Cytochrome P-450 CYP2C9
Cytochrome P-450 CYP2D6 Inhibitors
Databases, Nucleic Acid
Drug Interactions
Drug Prescriptions--economics
Enzyme Inhibitors--pharmacology
Female
Humans
Losartan--pharmacokinetics
Male
Medication Errors
Medication Systems, Hospital
Middle Aged
Prodrugs--metabolism
Sex Factors
Tramadol--pharmacokinetics