Specific locations of hydrophilic amino acids in constructed transmembrane ligands of the platelet-derived growth factor beta receptor.

Freeman-Cook, Lisa L

Specific locations of hydrophilic amino acids in constructed transmembrane ligands of the platelet-derived growth factor beta receptor. [electronic resource] - Journal of molecular biology Jan 2005 - 907-21 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0022-2836

10.1016/j.jmb.2004.10.072 doi


Amino Acid Sequence
Amino Acids--chemistry
Animals
Binding Sites
Cell Transformation, Neoplastic
Dimerization
Enzyme Inhibitors--pharmacology
Gene Library
Glutamine--genetics
Humans
Hydrophobic and Hydrophilic Interactions
Ligands
Mice
Models, Molecular
Molecular Sequence Data
Mutation--genetics
Protein Structure, Quaternary
Proteins--chemistry
Receptor, Platelet-Derived Growth Factor beta--antagonists & inhibitors
Sequence Alignment
Signal Transduction
Substrate Specificity
Tyrphostins--pharmacology