Synthesis of cyclopropane isosteres of the antiepilepsy drug vigabatrin and evaluation of their inhibition of GABA aminotransferase.
Wang, Zhiyong
Synthesis of cyclopropane isosteres of the antiepilepsy drug vigabatrin and evaluation of their inhibition of GABA aminotransferase. [electronic resource] - Journal of enzyme inhibition and medicinal chemistry Aug 2004 - 293-301 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
1475-6366
10.1080/14756360409162441 doi
4-Aminobutyrate Transaminase--antagonists & inhibitors
Anticonvulsants--chemical synthesis
Cyclopropanes--chemical synthesis
Drug Evaluation, Preclinical
Enzyme Inhibitors--chemical synthesis
Molecular Structure
Stereoisomerism
Vigabatrin--chemistry
Synthesis of cyclopropane isosteres of the antiepilepsy drug vigabatrin and evaluation of their inhibition of GABA aminotransferase. [electronic resource] - Journal of enzyme inhibition and medicinal chemistry Aug 2004 - 293-301 p. digital
Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
1475-6366
10.1080/14756360409162441 doi
4-Aminobutyrate Transaminase--antagonists & inhibitors
Anticonvulsants--chemical synthesis
Cyclopropanes--chemical synthesis
Drug Evaluation, Preclinical
Enzyme Inhibitors--chemical synthesis
Molecular Structure
Stereoisomerism
Vigabatrin--chemistry