Stimulus-coupled spatial restriction of extracellular signal-regulated kinase 1/2 activity contributes to the specificity of signal-response pathways.

Whitehurst, Angelique

Stimulus-coupled spatial restriction of extracellular signal-regulated kinase 1/2 activity contributes to the specificity of signal-response pathways. [electronic resource] - Molecular and cellular biology Dec 2004 - 10145-50 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.

0270-7306

10.1128/MCB.24.23.10145-10150.2004 doi


Active Transport, Cell Nucleus
Blotting, Western
Cell Nucleus--enzymology
Dose-Response Relationship, Drug
Enzyme Activation
Epidermal Growth Factor--metabolism
HeLa Cells
Humans
Immunoblotting
Ligands
Microscopy, Fluorescence
Mitogen-Activated Protein Kinase 1--metabolism
Mitogen-Activated Protein Kinase 3--metabolism
Mitogen-Activated Protein Kinases--metabolism
Phenotype
Proto-Oncogene Proteins c-fos--metabolism
Signal Transduction
Substrate Specificity
Tetradecanoylphorbol Acetate