Piperine is a potent inhibitor of nuclear factor-kappaB (NF-kappaB), c-Fos, CREB, ATF-2 and proinflammatory cytokine gene expression in B16F-10 melanoma cells.

Pradeep, C R

Piperine is a potent inhibitor of nuclear factor-kappaB (NF-kappaB), c-Fos, CREB, ATF-2 and proinflammatory cytokine gene expression in B16F-10 melanoma cells. [electronic resource] - International immunopharmacology Dec 2004 - 1795-803 p. digital

Publication Type: Journal Article

1567-5769

10.1016/j.intimp.2004.08.005 doi


Activating Transcription Factor 2
Alkaloids--pharmacology
Benzodioxoles
Cell Line, Tumor
Cell Nucleus--drug effects
Cell Proliferation--drug effects
Collagen--chemistry
Cyclic AMP Response Element-Binding Protein--antagonists & inhibitors
Cytokines--biosynthesis
Enzyme-Linked Immunosorbent Assay
Gelatin
Gene Expression--drug effects
Genes, fos--drug effects
Humans
Matrix Metalloproteinases--genetics
Melanoma, Experimental--metabolism
NF-kappa B--antagonists & inhibitors
Piperidines--pharmacology
Polyunsaturated Alkamides
RNA--biosynthesis
Reverse Transcriptase Polymerase Chain Reaction
Transcription Factors--antagonists & inhibitors