Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation.
Gestwicki, Jason E
Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation. [electronic resource] - Science (New York, N.Y.) Oct 2004 - 865-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
1095-9203
10.1126/science.1101262 doi
Alzheimer Disease--drug therapy
Amyloid beta-Peptides--chemistry
Animals
Cell Death--drug effects
Cell Survival--drug effects
Cells, Cultured
Congo Red--analogs & derivatives
Cross-Linking Reagents
Fluorescence
Hippocampus--cytology
In Situ Nick-End Labeling
Ligands
Microscopy, Fluorescence
Molecular Chaperones--metabolism
Molecular Structure
Neurites--ultrastructure
Neurons--cytology
Peptide Fragments--chemistry
Piperidines--chemical synthesis
Rats
Tacrolimus Binding Proteins--metabolism
Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation. [electronic resource] - Science (New York, N.Y.) Oct 2004 - 865-9 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
1095-9203
10.1126/science.1101262 doi
Alzheimer Disease--drug therapy
Amyloid beta-Peptides--chemistry
Animals
Cell Death--drug effects
Cell Survival--drug effects
Cells, Cultured
Congo Red--analogs & derivatives
Cross-Linking Reagents
Fluorescence
Hippocampus--cytology
In Situ Nick-End Labeling
Ligands
Microscopy, Fluorescence
Molecular Chaperones--metabolism
Molecular Structure
Neurites--ultrastructure
Neurons--cytology
Peptide Fragments--chemistry
Piperidines--chemical synthesis
Rats
Tacrolimus Binding Proteins--metabolism